2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. 9(R)-HODE

9(R)-HODE  (Synonyms: 9(R)-Hydroxyoctadecadienoic acid)

目录号: HY-113545
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9(R)-HODE 是一种单羟基脂肪酸和亚油酸代谢物。它由亚油酸通过 COX 和脂氧合酶 (LO) 形成。3,4 9(R)-HODE 诱导趋化性，增加趋化因子 (CC 基序) 受体 9 (CCR9) 和趋化因子 (CXC 基序) 受体 4 (CXCR4) 的水平，并抑制原代人单核细胞中 IL-6 的释放。当浓度为 25 μg/ml 时，它可抑制 CD3α 和 CD28 诱导的分离人外周血淋巴细胞增殖。

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9(R)-HODE Chemical Structure

9(R)-HODE Chemical Structure

CAS No. : 10075-11-3

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9(R)-HODE 相关抗体

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  • 生物活性

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生物活性

9(R)-HODE is a monohydroxy fatty acid and metabolite of linoleic acid. It is formed from linoleic acid by COX and lipoxygenase (LO).9(R)-HODE induces chemotaxis, increases the levels of chemokine (C-C motif) receptor 9 (CCR9) and chemokine (C-X-C motif) receptor 4 (CXCR4), and inhibits IL-6 release in primary human monocytes. It inhibits CD3α- and CD28-induced proliferation of isolated human peripheral blood lymphocytes when used at a concentration of 25 μg/mL.

分子量

296.44

Formula

C18H32O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

9(R)-HODE 相关分类

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  • 稀释计算器

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  • Do most proteins show cross-species activity?

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Keywords:

9(R)-HODE10075-11-39(R)-Hydroxyoctadecadienoic acidEndogenous MetaboliteInhibitorinhibitorinhibit

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