2. GPCR/G Protein
  3. Prostaglandin Receptor
  4. AGN 210676

AGN 210676  (Synonyms: Simenepag)

目录号: HY-14898
产品使用指南

摩尔计算器

AGN 210676 是一种有效的选择性前列腺素 EP2 激动剂，EC50 为 5 nM。详细信息请参考专利文献 US20070203222A1 中的化合物 example 23。

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AGN 210676 Chemical Structure

AGN 210676 Chemical Structure

CAS No. : 910562-15-1

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AGN 210676 相关抗体

Top Publications Citing Use of Products

查看 Prostaglandin Receptor 亚型特异性产品:

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DP EP FP IP TXA2/TP TXB2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AGN 210676 is a selective prostaglandin EP2 agonist extracted from patent US20070203222A1, Compound example 23, has an EC50 of 5 nM.

IC50 & Target[1]

EP2

5 nM (EC50)

hEP3

153 nM (EC50)

hDP receptor

7749 nM (EC50)

体外研究
(In Vitro)

AGN 210676 (Compound 23) also is a less potent agonist for recombinant human prostaglandin receptors hEP3A and hDP with EC50s of 153 nM and 7749 nM, respectively. AGN 210676 is useful for the treatment of glaucoma, ocular hypertension, inflammatory bowel disease, and the other diseases or conditions disclosed herein[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

AGN 210676 相关抗体:
分子量

431.55

Formula

C23H29NO5S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

AGN 210676 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AGN 210676910562-15-1SimenepagAGN210676AGN-210676Prostaglandin ReceptorInhibitorinhibitorinhibit

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目录号：
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