1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Acetic acid

Acetic acid  (Synonyms: 乙酸)

目录号: HY-Y0319 纯度: ≥99.0%
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Acetic acid 是一种短链脂肪酸 (SCFAs),其含量水平与中密度脂蛋白 (IDL-c) 的水平呈正相关。而 Propionic acid 与高密度脂蛋白 (HDL-P) 的水平呈负相关。Acetic acid 是大多数厌氧菌碳水化合物发酵代谢物,与肝脏中的“从头”脂肪生成和胆固醇生成刺激有关。Acetic acid 与 Propionic acid 的比例是宿主脂质谱状态的新型生物标志物。

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Acetic acid Chemical Structure

Acetic acid Chemical Structure

CAS No. : 64-19-7

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Acetic acid is a type of short-chain fatty acids (SCFAs) whose content levels are positively correlated with intermediate-density lipoprotein (IDL-c) levels. Propionic acid is negatively correlated with high-density lipoprotein (HDL-P) levels. Acetic acid is a carbohydrate fermentation metabolite of most anaerobic bacteria and is associated with stimulation of "de novo" lipogenesis and cholesterol production in the liver. The ratio of acetic acid to propionic acid is a novel biomarker of host lipid profile status[1].

IC50 & Target

Microbial Metabolite

 

Human Endogenous Metabolite

 

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HEK293 EC50
12 μM
Compound: Acetate
Agonist activity at human GPCR41 transfected in HEK293 cells assessed as [35S]GTPgammaS binding by scintillation counting method
Agonist activity at human GPCR41 transfected in HEK293 cells assessed as [35S]GTPgammaS binding by scintillation counting method
[PMID: 28745893]
HEK293 EC50
250 μM
Compound: Acetate
Agonist activity at human GPCR43 transfected in HEK293 cells assessed as [35S]GTPgammaS binding by scintillation counting method
Agonist activity at human GPCR43 transfected in HEK293 cells assessed as [35S]GTPgammaS binding by scintillation counting method
[PMID: 28745893]
分子量

60.05

Formula

C2H4O2

CAS 号
性状

液体(密度:1.049 g/cm3

颜色

Colorless to light yellow

中文名称

乙酸

初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料

纯度: ≥99.0%

参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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