2. GPCR/G Protein
  3. GCGR
  4. GLP-1(7-37)

GLP-1(7-37)  (Synonyms: 人胰高血糖素样肽-1)

目录号: HY-P0055 纯度: 99.82%
COA 产品使用指南

摩尔计算器

GLP-1(7-37) 是一种肠道胰岛素激素，可以增强葡萄糖诱导的胰岛素分泌。

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Custom Peptide Synthesis

GLP-1(7-37) Chemical Structure

GLP-1(7-37) Chemical Structure

CAS No. : 106612-94-6

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规格 价格 是否有货 数量
1 mg ￥2100
In-stock
5 mg ￥3600
In-stock
10 mg ￥5500
In-stock
25 mg 现货 询价
50 mg   询价  
100 mg   询价  

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Customer Review

Other Forms of GLP-1(7-37):

GLP-1(7-37) 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

GLP-1(7-37) is an intestinal insulinotropic hormone that augments glucose induced insulin secretion.

体内研究
(In Vivo)

GLP-1(7-37) (0.5, 5 or 50 pmol/min/kg) infused during the second hour of a 2-hour 11-mM hyperglycemic clamp produces a dose-related enhancement of the glucose-stimulated increase in plasma insulin concentration and an increased rate of glucose infusion in rats[2].
Infusion of GLP-1(7-37) (5 pmol/min/kg) from 1 hour through 7 hours produces a sustained increase in plasma insulin concentration relative to levels in rats infused with vehicle in rats with maintained glucose concentration at 11 mM[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Sprague-Dawley rats weighing 300 to 350 g with maintained plasma glucose concentration at 11 mM[2].
Dosage: 0.5, 5 or 50 pmol/min/kg.
Administration: IV during the second hour of a 2-hour 11-mmol/L hyperglycemic clamp.
Result: Produced a dose-related enhancement of the glucose-stimulated increase in plasma insulin concentration and an increased rate of glucose infusion.
Animal Model: Male Sprague-Dawley rats weighing 300 to 350 g with glucose IV at a variable rate for 7 hours to maintain plasma glucose concentration at 11 mM[2].
Dosage: 5 pmol/min/kg.
Administration: IV from 1 hour through 7 hours[2].
Result: Produced a sustained increase in plasma insulin concentration relative to levels in rats infused with vehicle.
分子量

3355.67

Formula

C151H228N40O47
CAS 号
性状

固体

颜色

White to off-white

Sequence

His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly
Sequence Shortening

HAEGTFTSDVSSYLEGQAAKEFIAWLVKGRG
中文名称

人胰高血糖素样肽-1
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

溶解性数据
细胞实验： 

0.1 M HCL 中的溶解度 : ≥ 50 mg/mL (14.90 mM)

80% Acetic acid/water 中的溶解度 : ≥ 10 mg/mL (2.98 mM)

DMSO 中的溶解度 : < 1 mg/mL (insoluble or slightly soluble)

H2O 中的溶解度 : < 0.1 mg/mL (insoluble)

* "≥" means soluble, but saturation unknown.

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 0.2980 mL 1.4900 mL 2.9800 mL
5 mM 0.0596 mL 0.2980 mL 0.5960 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料

纯度: 99.82%

COA (294 KB) LCMS (90 KB) 元素分析报告 (219 KB)

产品使用指南 (1538 KB)
参考文献

GLP-1(7-37) 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
80% Acetic acid/water / 0.1 M HCL 1 mM 0.2980 mL 1.4900 mL 2.9800 mL 7.4501 mL
0.1 M HCL 5 mM 0.0596 mL 0.2980 mL 0.5960 mL 1.4900 mL
10 mM 0.0298 mL 0.1490 mL 0.2980 mL 0.7450 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GLP-1(7-37)106612-94-6人胰高血糖素样肽-1GCGRGlucagon ReceptorInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-P0055
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