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  3. Biochemical Assay Reagents
  4. Gelucire 44/14

Gelucire 44/14  (Synonyms: 月桂酸聚乙二醇甘油酯)

目录号: HY-Y1892 纯度: ≥96.0%
COA 产品使用指南

摩尔计算器

Gelucire 44/14 是一种强效且安全的吸收促进剂，用于改善通过肺部递送的难吸收活性分子的吸收包括胰岛素和降钙素在内。

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Gelucire 44/14 Chemical Structure

Gelucire 44/14 Chemical Structure

CAS No. : 121548-04-7

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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100 g ￥1300
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Customer Review

Gelucire 44/14 相关抗体

Top Publications Citing Use of Products

MCE 顾客使用本产品发表的 1 篇科研文献

  • 生物活性

  • 实验参考方法

  • 纯度 & 产品资料

  • 参考文献

生物活性

Gelucire 44/14 is a potential and safe absorption enhancer for improving the absorption of poorly absorbable agents including insulin and calcitonin by pulmonary delivery.

体内研究
(In Vivo)

Gelucire 44/14 is a potential and safe absorption enhancer for improving the absorption of poorly absorbable drugs including insulin and calcitonin by pulmonary delivery. It is found that pulmonary absorptions of FD4, FD10 and FD70 are enhanced in different degree by Gelucire 44/14 in a concentration-dependent manner, and the maximal absorption-enhancing effect is obtained when the concentration of Gelucire 44/14 reaches to 2.0% (w/v). It is also found that the absorption enhancing ability of Gelucire Gelucire 44/14 is correlated with the molecular weight of model drugs, and the highest absorption enhancement ratio of Gelucire Gelucire 14/44 is observed when the molecular weight of model drugs reaches to nearly 10000 Da[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
CAS 号
性状

油状物

颜色

Off-white to light yellow

中文名称

月桂酸聚乙二醇甘油酯
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Pure form -20°C 3 years
4°C 2 years
溶解性数据
细胞实验： 

Ethanol 中的溶解度 : 100 mg/mL (超声助溶)

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料

纯度: ≥96.0%

COA (189 KB)

产品使用指南 (1538 KB)
参考文献
Animal Administration
[1]

Male Sprague Dawley rats are used to evaluate the pulmonary membrane toxicity of Gelucire 44/14. PBS (pH 7.4) with or without Gelucire 44/14 are directly administered to the tracheae of the rats according to the in-situ pulmonary absorption experiments. Four hours later, the rats are bled from the abdominal aorta, and then PBS (pH7.4) is perfused into the rat lung along the trachea. Afterwards, bronchoalveolar lavage fluid (BALF) of rat in each group is collected and kept in ice immediately until determination[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
参考文献

Gelucire 44/14 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Gelucire 44/14121548-04-7月桂酸聚乙二醇甘油酯Biochemical Assay ReagentsInhibitorinhibitorinhibit

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目录号：
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