1. Metabolic Enzyme/Protease Membrane Transporter/Ion Channel
  2. Endogenous Metabolite Potassium Channel
  3. Guanosine 5'-diphosphate

Guanosine 5'-diphosphate  (Synonyms: GDP)

目录号: HY-113066
产品使用指南

Guanosine 5'-diphosphate (GDP) 是一种核苷二磷酸,可激活 5'-三磷酸腺苷敏感的 K+ 通道。Guanosine 5'-diphosphate 是一种潜在的铁动员剂,可阻断铁调素-铁转运蛋白 (hepcidin-ferroportin) 相互作用并调节 IL-6/stat-3 通路。Guanosine 5'-diphosphate 可用于炎症研究,如炎症性贫血 (AI)。

在相同的摩尔浓度下,化合物盐形式与游离形式有相同的生物活性,但盐形式 Guanosine 5'-diphosphate disodium salt 通常具有更好的水溶性和稳定性。

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Guanosine 5'-diphosphate Chemical Structure

Guanosine 5'-diphosphate Chemical Structure

CAS No. : 146-91-8

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K+ channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI)[1][2].

IC50 & Target[2]

Human Endogenous Metabolite

 

Clinical Trial
分子量

443.20

Formula

C10H15N5O11P2

CAS 号
中文名称

鸟苷-5’-二磷酸

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Guanosine 5'-diphosphate
目录号:
HY-113066
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