2. Peptides
  3. 多肽修饰

多肽修饰

多肽修饰通过修饰多肽主链及侧链结构，改变多肽的理化性质，进而改善其生物利用效率。MCE 配备强大的技术团队，可提供 300+ 种修饰，满足您多样化的研究需求。

N 端修饰

  • •Ac
  • •Allyl
  • •Cholesteryl-
  • •N-Propargylglycine-
  • •Fmoc
  • •Acryl
  • •Fructose-
  • •Ad
  • •CBZ
  • •Alloc
  • •Glucose-
  • •BPS-
  • •Boc
  • •Pyr
  • •DMAP-Ac
  • •Morpholine-4-carbonyl-
  • •Bz
  • •D-Pyr
  • •NTriAc
  • •Trans-Cinnamoyl
  • •Bz (5-NH2,2-NO2)
  • •LA-
  • •PhAc
  • •2-Furoyl
  • •Bz (4-F)
  • •Mpa-
  • •Py-Ac
  • •Methacryl-
  • •Bz (4-NO2)
  • •Tos
  • •N-Amidinoglycine
  • •BPA-

C 端修饰

  • •-pNA
  • •-OMe
  • •-ONP
  • •-OSu
  • •-NH2
  • •-OEt
  • •-AMC
  • •-NHMe
  • •-ol
  • •-OBzl
  • •-AFC
  • •-NHEt

脂肪酸化

  • •For
  • •MeOSuc
  • •5-Hexynoic acid
  • •F-Lau-
  • •MeOCO
  • •Iba
  • •Heptanedioic acid
  • •Myr-
  • •2-Br-Ac
  • •pentenoic acid
  • •Oct-
  • •F-Myr-
  • •2-Cl-Ac
  • •pentinoyl
  • •F-Oct-
  • •Pentadeconyl-
  • •2-I-Ac
  • •Hex-
  • •Dec-
  • •Pal-
  • •OH-Ac
  • •5-heptenoic acid
  • •Sebacic acid
  • •Cys (Pal)
  • •3-Bromopropionyl
  • •Trans-3-hexenoyl-
  • •F-Dec-
  • •Pam3C-
  • •But-
  • •Linoletic-
  • •Undecyl-
  • •Ste-
  • •Suc
  • •10,12-Pentacosadiynoic acid
  • •Lau-
  • •Octanedioic acid

甲基化

  • •Lys (Me)
  • •Arg (Me)
  • •Tyr (Me)
  • •Tyr (Et)
  • •Lys (Me2)
  • •Arg (Me2)asymmetrical
  • •Thr (Me)
  • •D-Tyr (Et)
  • •Lys (Me3)
  • •Arg (Me2) symmetrical
  • •Ser (Me)
  •  

磷酸化

  • •pSer
  • •D-pSer
  • •Di-sites in sequence
  • •4-sites in sequence
  • •pTyr
  • •D-pTyr
  • •Tri-sites in sequence
  • •5-sites in sequence
  • •pThr
  • •D-pThr
  •  
  •  

支肽

  • •Symmetric 2 Branches
  • •Symmetric 4 Branches
  • •Symmetric 8 Branches
  • •Lys symmetric 2 Branches
  • •Lys symmetric 4 Branches
  • •Lys symmetric 8 Branches
  • •Orn symmetric 2 Branches
  • •Orn symmetric 4 Branches
  • •Orn symmetric 8 Branches
  • •Glu 2 Branches (Pure)
  • •Glycerol 3 Branches ester
  • •Thr (Peptide2)
  • •Ser (Peptide2)
  • •Lys (Peptide2)
  •  
  •  

环肽

  • •Mono Disulfide bridge
  • •Double Disulfide bridge
  • •Triple Disulfide bridge
  • •Random Triple Disulfide bridge
  • •Same Sequence Inter-Disulfide bridge by Cys oxidation
  • •Different Sequence Inter-Disulfide bridge by Cys oxidation
  • •Oxidation between Se-Cys
  • •Amide Cyclic (end)
  • •Amide Cyclic (side chain) by Lys
  • •Amide Cyclic (side chain) by Orn
  •  
  •  

荧光/染料标记

  • •Biotin-
  • •FITC-
  • •Dansyl-
  • •Lys (Dnp)
  • •DeThioBiotin
  • •-ED-FITC
  • •-EDDansyl
  • •D-Lys (Dnp)
  • •-EDBiotin
  • •-Lys (FITC)-
  • •-Lys (Dansyl)-
  • •Dab (Dnp)
  • •Glu (Biotin-PEG2)
  • •-Lys (FITC)
  • •-Lys (Dansyl)
  • •Dap (Dnp)
  • •-Lys (Biotin)-
  • •Lys (Ahx-FITC)
  • •Dansli-e-Lys
  • •-EDDnp
  • •-Lys (Biotin)
  • •FITC-e-Lys
  • •Dansyl-Ahx-
  • •-Lys (LC-Biotin)-
  • •FITC-Ahx-
  • •5-FAM-
  • •-Lys (LC-Biotin)
  • •5-TAMRA-
  • •5,6-FAM
  • •Biotin-e-Lys
  • •5 (6)-TAMTA-
  • •6’FAM
  • •Lys (S-S-Biotin)
  • •-EDYAMRA
  • •-ED-5-FAM
  • •Biotin-Ahx-
  • •-Lys (TAMRA)-
  • •-Lys (5-FAM)-
  • •Orn (Bio)
  • •-Lys (5-TAMRA)
  • •Lys (5,6-FAM)
  • •MCA-
  • •5-TAMRA-e-Lys
  • •-Lys (5-FAM)
  • •-Lys (MCA)-
  • •5-TAMRA-Acp
  • •5-FAM-E-Lys
  • •-Lys (MCA)
  • •5-FAM-Ahx-
  • •Lys (MCA)-
  •  
  •  

BSA、KLH、OVA 偶联

  • •BSA-Peptide N terminus
  • •KLH-Peptide N terminus
  • •OVA-Peptide N terminus
  • •BSA-Peptide C terminus
  • •KLH-Peptide C terminus
  • •OVA-Peptide C terminus
  • •BSA-Peptide via Cys
  • •KLH-Peptide via Cys
  • •OVA-Peptide via Cys
  •  
  •  
  •  

Phe & Tyr 衍生物

  • •D-2-Cl-Phe
  • •D-4-F-Phe
  • •L-2-Me-Phe
  • •L-3-I-Tyr
  • •L-2-Cl-Phe
  • •L-4-F-Phe
  • •D-4-Me-Phe
  • •D-3,5-DiI-Tyr
  • •D-3-Cl-Phe
  • •D-4-NO2-Phe
  • •L-4-Me-Phe
  • •L-3,5-DiI-Tyr
  • •L-3-Cl-Phe
  • •L-4-NO2-Phe
  • •D-4-NH2-Phe
  • •D-3-NO2-Tyr
  • •D-4-Cl-Phe
  • •D-4-I-Phe
  • •L-4-NH2-Phe
  • •L-3-NO2-Tyr
  • •L-4-Cl-Phe
  • •L-4-I-Phe
  • •D-3-Cl-Tyr
  • •D-3,5-DiNO2-Tyr
  • •D-3,4-DiCl-Phe
  • •D-3-CN-Phe
  • •L-3-Cl-Tyr
  • •L-3,5-DiNO2-Tyr
  • •L-3,4-DiCl-Phe
  • •L-3-CN-Phe
  • •D-3,5-DiCl-Tyr
  • •L-3-F-Tyr
  • •D-4-Br-Phe
  • •D-4-CN-Phe
  • •L-3,5-DiCl-Tyr
  • •L-4-NO2-Phg
  • •L-4-Br-Phe
  • •L-4-CN-Phe
  • •D-3,5-DiBr-Tyr
  • •D-4-NO2-Phg
  • •D-3-F-Phe
  • •D-2-Me-Phe
  • •L-3,5-DiBr-Tyr
  • •L-3,5-DiF-Phe
  • •L-3-F-Phe
  • •D-3-I-Tyr
  •  
  •  

Linker

  • •Gly
  • •Ava
  • •AEA
  • •GABA
  • •Beta-Ala
  • •Ahx
  • •Ado
  • •Mini-PEG
  • •Mini-PEG2
  • •Mini-PEG3
  • •PEG4
  •  

树脂

  • •peptide on Wang Resin
  • •peptide on 2-CTC Resin
  • •peptide on Rink Amide AM Resin
  • •peptide on Rink Amide MBHA Resin

D 型氨基酸

  • •D-Ala
  • •D-Lys
  • •D-Glu
  • •D-Tyr
  • •D-Arg
  • •D-Met
  • •D-Gln
  • •D-Thr
  • •D-Asp
  • •D-Pro
  • •D-His
  • •D-Trp
  • •D-Asn
  • •D-Phe
  • •D-Leu
  • •D-Val
  • •D-Cys
  • •D-Ser
  •  
  •  

同型氨基酸

  • •Har
  • •HomoCit
  • •beta-HomoMet
  • •beta-HomoSer
  • •D-Har
  • •D-HomoCit
  • •beta-HomoPro
  • •beta-HomoThr
  • •Hcy
  • •HomoLeu
  • •beta-HomoVal
  • •beta-HomoTrp
  • •HPh
  • •HomoPro
  • •beta-HomoAsp
  • •beta-HomoTyr
  • •D-HPh
  • •D-HomoPro
  • •beta-HomoAsn
  • •Azidohomoalanine
  • •Hse
  • •beta-HomoIle
  • •beta-HomoGlu
  • •beta-HomoAla
  • •D-Hse
  • •beta-HomoLeu
  • •beta-HomoGln
  • •beta-HomoPhe

特殊氨基酸

  • •beta-Asp
  • •3-Thi
  • •D-Chg
  • •Cys (pMeBzl)
  • •D-beta-Asp
  • •Aib
  • •Ac6c
  • •Cys (pMeOBzl)
  • •gamma-Glu
  • •Abu
  • •Dab
  • •Oic
  • •D- gamma-Glu
  • •D-Abu
  • •Dap
  • •Tic
  • •Cys (Cam)
  • •Hyp
  • •Pra
  • •D-Tic
  • •D-Cys (Cam)
  • •Phg
  • •D-Pra
  • •Cys (Bzl)
  • •Cys (Acm)
  • •D-Phg
  • •Allo-Thr
  • •Epsilon-Lys
  • •Cys (tBu)
  • •Nva
  • •D-Allo-Thr
  • •D-Epsilon-Lys
  • •Cys (StBu)
  • •D-Nva
  • •Gly (allyl)
  • •5-ASA
  • •Met (O)
  • •Nle
  • •D-Gly (allyl)
  • •Bpa
  • •D-Met (O)
  • •D-Nle
  • •Cys (Pyrene-maleimide)
  • •Pip
  • •Cys (SNO)
  • •Cit
  • •D-1-Nal
  • •Nip
  • •Met (O)2
  • •D-Cit
  • •L-1-Nal
  • •2-Aze
  • •D-Met (O)2
  • •Orn
  • •D-2-Nal
  • •3-Aze
  • •Lys (Ac)
  • •D-Orn
  • •L-2-Nal
  • •[Psi (CH2NH)]
  • •Ac-Lys
  • •Pen
  • •D-2-Pal
  • •[CS-NH]
  • •Lys (Dde)
  • •D-Pen
  • •L-2-Pal
  • •Se-Met
  • •Tle
  • •Cpg
  • •D-3-Pal
  • •Se-Cys
  • •Ser (Octanoic acid)
  • •Cha
  • •L-3-pal
  • •DOPA
  • •Ser (Lipoic acid)
  • •D-Cha
  • •D-4-Pal
  • •isoGln
  • •D-Ser (Octanoic acid)
  • •Chg
  • •L-4-Pal
  • •D-isoGln
  • •Arg (Boc2)
  • •Asp-OMe
  • •D-Glu (OtBu)
  • •Lys (Z)
  • •Arg (NO2)
  • •Asp-OtBu
  • •Gln (Trt)
  • •Ser (Bzl)
  • •Arg (Z2)
  • •Asn (Trt)
  • •His (Boc)
  • •Ser (Trt)
  • •Arg (pbf)
  • •Cys (MMt)
  • •His (Trt)
  • •Ser (tBu)
  • •D-Arg (pdf)
  • •Cys (Trt)
  • •Tyr (propargyl)
  • •Tyr (tBu)
  • •Asp (Oall)
  • •D-Cys (Trt)
  • •Lys (Boc)
  • •Asp (OBn)
  • •Glu (Oall)
  • •Lys (DMT)
  • •D-Tyr (tBu)
  • •Asp (OBzl)
  • •Glu (OBzl)
  • •Lys (Fomc)
  • •Thr (tBu)
  • •Asp (OMe)
  • •Glu (OMe)
  • •Lys (Mtt)
  • •Trp (Boc)
  • •Asp (OtBu)
  • •Glu (OtBu)
  • •Lys (Trt)
  • •Trp (Farnesyl)
  •  
注意：

1.  以上信息仅供参考，您提供的多肽修饰定制需求将提交至实验室评估。

2.   如有未列入表格中的多肽修饰需求，您可以发邮件至 sales@MedChemExpress.cn 进行咨询。.

 

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