Indoleamine 2,3-Dioxygenase (IDO) Inhibitors

IDO1, IC₅₀: 71.8 nM

IDO, Ki: 19 μM

IDO1, IC₅₀: 1.1 nM

IDO-1, IC₅₀: 3 μM (HEK 293-hIDO-1)
IDO-1, IC₅₀: 157 μM (rhIDO-1)

IDO

IDO, IC₅₀: 6.3 μM
IDO, Ki: 5.8 μM

IDO-1

IDO1, IC₅₀: 38 nM

IDO, EC₅₀: 75 nM
IDO, Ki: 7 nM

IDO1, IC₅₀: 7.0 μM

IDO-1, IC₅₀: 3 μM (HEK 293-hIDO-1)
IDO-1, IC₅₀: 157 μM (rhIDO-1)

rhIDO2, IC₅₀: 1.8 μM
rhIDO2, Ki: 0.97 μM

IDO1

IDO1, IC₅₀: 3.53 μM

IDO1, IC₅₀: 411 nM

IDO2, IC₅₀: 112

IDO, IC₅₀: 4.52 nM (in HeLa cell)

IDO, IC₅₀: 67 nM
IDO, IC₅₀: 19 nM (in HeLa cell)

IDO1, DC₅₀: 2.84 μM
IDO1, IC₅₀: 1.07 μM

IDO, IC₅₀: 290 nM
IDO, IC₅₀: 98 nM (in HeLa cell)

IDO-1

IDO-1, IC₅₀: 3 μM (HEK 293-hIDO-1)
IDO-1, IC₅₀: 157 μM (rhIDO-1)

IDO, IC₅₀: 59 nM
IDO, IC₅₀: 12 nM (in HeLa cell)

IDO1

IDO, IC₅₀: 1-10 μM

IDO, IC₅₀: 1-10 μM

IDO, IC₅₀: 1 μM

IDO, IC₅₀: 6.3 μM
IDO, Ki: 5.8 μM

IDO1, IC₅₀: 28 nM

IDO2, IC₅₀: 144 nM

IDO1, IC₅₀: 233 nM

IDO1

IDO1, IC₅₀: 0.44 μM (in hela cells)

IDO1, IC₅₀: 127 nM

IDO1, IC₅₀: 127 nM

IDO1, IC₅₀: 330 nM

IDO1

IDO1, Kd: 640 nM

IDO1, IC₅₀: 30 nM

IDO1, EC₅₀: 396.9 nM

IDO1, IC₅₀: 0.17 μM

IDO1

IDO1, IC₅₀: 81 nM

IDO-1

IDO1, Ki: 0.23 μM

IDO1, IC₅₀: 0.64 μM

IDO1, IC₅₀: 0.084 μM

IDO, IC₅₀: 55 nM

IDO1, IC₅₀: 1.1 nM

IDO1, IC₅₀: 8 μM

IDO1, IC₅₀: 69.0 nM

IDO, IC₅₀: 11 nM
IDO, IC₅₀: 1.8 nM (in Hela cell)

IDO, IC₅₀: 180 nM
IDO, IC₅₀: 14 nM (in Hela cell)