1. Immunology/Inflammation
  2. SOD
  3. δ-Sleep Inducing Peptide

δ-Sleep Inducing Peptide  (Synonyms: Delta-Sleep Inducing Peptide)

目录号: HY-P1501
产品使用指南

δ-Sleep Inducing Peptide 是一种神经肽,具有抗氧化和抗焦虑作用。

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Custom Peptide Synthesis

δ-Sleep Inducing Peptide Chemical Structure

δ-Sleep Inducing Peptide Chemical Structure

CAS No. : 62568-57-4

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

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δ-Sleep Inducing Peptide 的其他形式现货产品:

Customer Review

Other Forms of δ-Sleep Inducing Peptide:

  • 生物活性

  • 实验参考方法

  • 纯度 & 产品资料

  • 参考文献

生物活性

δ-Sleep Inducing Peptide is a neuropeptide, with antioxidant and anxiolytic properties.

体内研究
(In Vivo)

δ-Sleep Inducing Peptide (DSIP) 导致兔子体内纺锤体活动增加,心脏和呼吸频率适度降低[1]。δ-Sleep Inducing Peptide (DSIP; 40-360 μg/kg, 腹腔注射) 在 40 μg/kg 剂量下,增加大鼠体内过氧化氢酶和超氧化物歧化酶 (SOD) 活性以及急性应激大鼠肝脏匀浆中的丙二醛 (MDA) 浓度,但在 120 μg/kg 和 360 μg/kg 时观察到相反的效果[2]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

848.81

Formula

C35H48N10O15

CAS 号
Sequence

Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu

Sequence Shortening

WAGGDASGE

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
细胞实验: 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

  Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.  Recommended solution:

Overall charge of peptide Details
Negative (<0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, add NH4OH (<50 μL).
3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
纯度 & 产品资料
参考文献
Animal Administration
[2]

Rats[2]
Experiments are performed on male Wistar rats (n = 100) weighing 250-280 g. The animals are divided into groups (10 specimens per group). They are maintained under standard vivarium conditions and have free access to water and food (12:12-h light/dark regimen). δ-Sleep Inducing Peptide is dissolved in physiological saline and injected intraperitoneally 60 min before each stress exposure. Control animals receive an equivalent volume of physiological saline (1 mL/kg). The liver is homogenized in ice-cold physiological saline and centrifuged. The content of LPO products and activities of antioxidant enzymes are measured in the supernatant. LPO intensity is evaluated by malonic dialdehyde (MDA) concentration. Activities of superoxide dismutase (SOD) and catalase are measured spectrophotometrically. The total antioxidant activity (TAA) is evaluated by the method based on inhibition of ascorbate-induced and iron-induced oxidation of Tween-80 to MDA. The assay is conducted on a BTS-330 biochemical analyzer[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
δ-Sleep Inducing Peptide
目录号:
HY-P1501
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