2. Immunology/Inflammation
  3. CD3
  4. Etentamig

Etentamig  (Synonyms: ABBV-383; TNB 383B)

目录号: HY-P990785 纯度: 99%
COA 技术支持

Etentamig 是一种 BCMA × CD3 双特异性 T 细胞结合器 (BiTE)，可抑制 B 细胞成熟蛋白活性 (BCMA) 和激活 T 细胞表面糖蛋白 CD3 复合体。Etentamig 可用于多发性骨髓瘤，免疫球蛋白轻链淀粉样变性及心血管疾病领域研究。

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规格 价格 是否有货 数量
1 mg ￥15500
In-stock
5 mg   询价  
10 mg   询价  

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Etentamig 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Etentamig is a BCMA × CD3 bispecific T-cell engager (BiTE) that can inhibit the activity of B-cell maturation antigen (BCMA) and activate the T-cell surface glycoprotein CD3 complex. Etentamig can be used for research in multiple myeloma, immunoglobulin light chain amyloidosis, and cardiovascular diseases[1].

同型

Human IgG4 kappa
推荐同型对照抗体
性状

液体

颜色

Colorless to light yellow

运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
  • Loaded ABBV-383 on AHC2 biosensor, can bind BCMA/TNFRSF17 Protein, Human (HEK293, His, HY-P72847) with an affinity constant of 1.731E-11 M as determined in BLI assay.
  • Loaded ABBV-383 on AHC2 biosensor, can bind CD3D-CD3E Heterodimer Protein, Human (HEK293, Fc-Flag&Fc-His, HY-P70434) with an affinity constant of 3.674E-07 M as determined in BLI assay.
纯度 & 产品资料
参考文献

Etentamig 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

EtentamigABBV-383 TNB 383BABBV383ABBV 383CD3Cluster of differentiation 3CancerImmunoglobulin light chain amyloidosisCardiovascular diseasesInhibitorinhibitorinhibit

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