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  4. AC-178335

AC-178335 是一种 SRIF 拮抗剂,其 Ki 值为 172 nM。AC-178335 可在体外阻断 SRIF 对腺苷酸环化酶的抑制 (IC50=5.1 μM)。AC-178335 可诱导麻醉大鼠的 GH 释放。

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AC-178335 Chemical Structure

AC-178335 Chemical Structure

CAS No. : 212966-15-9

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AC-178335 is a SRIF antagonist, with a Ki of 172 nM. AC-178335 blocks SRIF inhibition of adenylate cyclase in vitro (IC50=5.1 μM). AC-178335 induces GH release in anesthetized rats[1].

分子量

946.11

Formula

C49H63N13O7

CAS 号
Sequence

Ac-{d-(His-Phe-Ile-Arg-Trp-Phe)}-NH2

Sequence Shortening

Ac-{d-(HFIRWF)}-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
AC-178335
目录号:
HY-125673
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