1. PROTAC
  2. PROTAC Linkers
  3. Acid-PEG4-C2-Boc

Acid-PEG4-C2-Boc 是一种 PROTAC linker,属于 PEGAlkyl/ether 类,可以用于合成抑制 mTORPROTAC

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Acid-PEG4-C2-Boc Chemical Structure

Acid-PEG4-C2-Boc Chemical Structure

CAS No. : 1835759-85-7

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规格 价格 是否有货
25 mg ¥200
询问价格 & 货期
50 mg ¥317
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100 mg ¥380
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250 mg ¥624
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500 mg ¥1244
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查看 PROTAC Linkers 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Acid-PEG4-C2-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs for the inhibition of mTOR[1].

IC50 & Target

PEGs

 

Alkyl/ether

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

350.40

Formula

C16H30O8

CAS 号
性状

液体(密度:1.107±0.06 g/cm3

颜色

Colorless to light yellow

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料
参考文献

Acid-PEG4-C2-Boc 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Acid-PEG4-C2-Boc
目录号:
HY-23167
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