1. GPCR/G Protein Neuronal Signaling
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  3. Adrogolide hydrochloride

Adrogolide hydrochloride  (Synonyms: ABT-431 hydrochloride; DAS-431 hydrochloride)

目录号: HY-118956
产品使用指南

Adrogolide hydrochloride (ABT-431 hydrochloride) 是一种化学稳定的前药,可转化为多巴胺 D1 受体激动剂 A-86929。Adrogolide hydrochloride 可改善狨猴模型中 MPTP (HY-15608) 诱发的帕金森病,降低运动障碍倾向。Adrogolide hydrochloride 可以在猴子体内逆转 Risperidone (HY-11018)-诱导的认知障碍。

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Adrogolide hydrochloride Chemical Structure

Adrogolide hydrochloride Chemical Structure

CAS No. : 166591-11-3

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Adrogolide hydrochloride (ABT-431 hydrochloride) is a chemically stable prodrug that can convert to the dopamine D1 receptor agonist A-86929. Adrogolide hydrochloride ameliorates the MPTP (HY-15608)-induced Parkinson's Disease in marmoset model, reduces the dyskinesias tendency. Adrogolide hydrochloride reverses Risperidone (HY-11018)-induced cognitive deficits in monkey[1].

分子量

435.96

Formula

C22H26ClNO4S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Adrogolide hydrochloride
目录号:
HY-118956
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