2. Metabolic Enzyme/Protease
  3. Glycosidase
  4. Afegostat hydrochloride

Afegostat hydrochloride  (Synonyms: D-Isofagomine hydrochloride; Isofagomine hydrochloride)

目录号: HY-14829A
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Afegostat hydrochloride (D-Isofagomine hydrochloride)是一种强效的β-galactosidase抑制剂，具有改善GM1-gangliosidosis和Morquio B型疾病相关突变的活性。Afegostat hydrochloride能够诱导GM1-gangliosidosis患者成纤维细胞中突变β-galactosidase的成熟。Afegostat hydrochloride还可促进中角质硫酸盐和低聚糖负荷的减少。

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Afegostat hydrochloride Chemical Structure

Afegostat hydrochloride Chemical Structure

CAS No. : 161302-93-8

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Afegostat hydrochloride 的其他形式现货产品:

Other Forms of Afegostat hydrochloride:

Afegostat hydrochloride 相关抗体

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  • 生物活性

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生物活性

Afegostat hydrochloride (D-Isofagomine hydrochloride) is a potent β-galactosidase inhibitor with activity ameliorating GM1-gangliosidosis and Morquio B disease-associated mutations. Afegostat hydrochloride is able to induce the maturation of mutant β-galactosidase in fibroblasts from patients with GM1-gangliosidosis. Afegostat hydrochloride also promotes the reduction of keratin sulfate and oligosaccharide load in patient cells[1].

分子量

183.63

Formula

C6H14ClNO3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Afegostat hydrochloride 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Afegostat161302-93-8D-IsofagomineIsofagomineGlycosidaseInhibitorinhibitorinhibit

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