1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Aglepristone

Aglepristone是一种合成类固醇抗孕激素,具有流产的活性。Aglepristone被专门用作怀孕动物的流产剂。Aglepristone在中期妊娠中被证明是一种安全有效的流产剂。Aglepristone可导致妊娠终止,并且不会引起胎儿吸收。Aglepristone的处理过程中,观察到促乳素的血浆浓度升高,而孕酮水平保持不变。Aglepristone的使用还导致了黄体功能的早期停止和发情间隔的缩短。

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Aglepristone Chemical Structure

Aglepristone Chemical Structure

CAS No. : 124478-60-0

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  • 生物活性

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生物活性

Aglepristone is a synthetic steroidal antiprogestin with abortifacient activity. Aglepristone is used exclusively as an abortifacient in pregnant animals. Aglepristone has been shown to be a safe and effective abortifacient in the second trimester of pregnancy. Aglepristone causes termination of pregnancy and does not cause fetal resorption. During aglepristone treatment, an increase in plasma concentrations of prolactin was observed, while progesterone levels remained unchanged. The use of aglepristone also resulted in early arrest of corpus luteum function and a shortening of the estrus interval[1].

分子量

431.61

Formula

C29H37NO2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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产品名称:
Aglepristone
目录号:
HY-135730
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