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  4. AI-10-104

AI-10-104 是一种 runt 相关转录因子 (RUNX) 抑制剂，可增强骨髓瘤细胞的细胞毒性。

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AI-10-104 Chemical Structure

AI-10-104 Chemical Structure

CAS No. : 1881276-00-1

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AI-10-104 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AI-10-104 is an inhibitor for runt-related transcription factor (RUNX), which enhances the cytotoxicity in myeloma cells[1].

体外研究
(In Vitro)

AI-10-104 (0-10 μM) 通过解离 RUNXs-IKZFs 复合物抑制 RUNX，增强来那度胺 (CC-5013) 的抗增殖作用及其对骨髓瘤细胞的细胞毒性[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

AI-10-104 相关抗体:

Western Blot Analysis[1]

Cell Line: HEK293T
Concentration: 0-10 μM
Incubation Time:
Result: Decreased levels of IKZF3 and CBFβ.

Cell Proliferation Assay[1]

Cell Line: OPM-1 cells, KMS-11 and U266 cells
Concentration: 1 μM
Incubation Time:
Result: Maintained the cell viability, inhibited proliferation of OPM-1 cells in a moderate effect.
分子量

309.24

Formula

C14H10F3N3O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

AI-10-104 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AI-10-1041881276-00-1Othersmultiple myelomaOPM-1KMS-11U266HEK293TInhibitorinhibitorinhibit

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产品名称：
AI-10-104
目录号：
HY-122657
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