2. Others
  3. Others
  4. AKR1C3-IN-6

AKR1C3-IN-6 (Compound 1) 是一种有效的、选择性的 AKR1C3 抑制剂，对 AKR1C3 和 AKR1C2 的 IC50 分别为 0.31 μM 和 73.23 μM。AKR1C3-IN-6 具有抗肿瘤活性。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

AKR1C3-IN-6 Chemical Structure

AKR1C3-IN-6 Chemical Structure

CAS No. : 2137881-54-8

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Customer Review

AKR1C3-IN-6 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 实验参考方法

  • 纯度 & 产品资料

  • 参考文献

生物活性

AKR1C3-IN-6 (Compound 1) is a potent, selective AKR1C3 inhibitor with IC50 values of 0.31 μM and 73.23 μM against AKR1C3 and AKR1C2, respectively. AKR1C3-IN-6 shows antitumor activity[1].

IC50 & Target

IC50: 0.31 μM (AKR1C3), 73.23 μM (AKR1C2)[1]
细胞效力
(Cellular Effect)
Cell Line Type Value Description References
CWR22R IC50
81.4 μM
Compound: 1
Antiproliferative activity against human 22Rv1 cells expressing AKR1C3 assessed as inhibition of cell growth incubated for 72 hrs by SRB assay
Antiproliferative activity against human 22Rv1 cells expressing AKR1C3 assessed as inhibition of cell growth incubated for 72 hrs by SRB assay
[PMID: 35447434]
CWR22R IC50
81.4 μM
Compound: 1
Antiproliferative activity against human 22Rv1 cells after 72 hrs by sulforhodamine B colorimetric assay
Antiproliferative activity against human 22Rv1 cells after 72 hrs by sulforhodamine B colorimetric assay
[PMID: 29602039]
CWR22R IC50
81.4 μM
Compound: 8
Antiproliferative activity against human 22Rv1 cells after 72 hrs by sulforhodamine B colorimetric proliferation assay
Antiproliferative activity against human 22Rv1 cells after 72 hrs by sulforhodamine B colorimetric proliferation assay
[PMID: 28881288]
体外研究
(In Vitro)

AKR1C3-IN-6 (Compound 1) shows antiproliferative activity with an IC50 of 81.40 ± 2.29 μM against prostate cancer cell line 22rv1[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

AKR1C3-IN-6 相关抗体:
分子量

392.33

Formula

C18H15F3N4O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献
Cell Assay

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
参考文献

AKR1C3-IN-6 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AKR1C3-IN-62137881-54-8Others22rv1prostate cancerantitumorInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
AKR1C3-IN-6
目录号：
HY-146573
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z