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  4. AKR1C3-IN-6

AKR1C3-IN-6 (Compound 1) 是一种有效的、选择性的 AKR1C3 抑制剂，对 AKR1C3 和 AKR1C2 的 IC50 分别为 0.31 μM 和 73.23 μM。AKR1C3-IN-6 具有抗肿瘤活性。

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AKR1C3-IN-6 Chemical Structure

AKR1C3-IN-6 Chemical Structure

CAS No. : 2137881-54-8

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AKR1C3-IN-6 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 实验参考方法

  • 纯度 & 产品资料

  • 参考文献

生物活性

AKR1C3-IN-6 (Compound 1) is a potent, selective AKR1C3 inhibitor with IC50 values of 0.31 μM and 73.23 μM against AKR1C3 and AKR1C2, respectively. AKR1C3-IN-6 shows antitumor activity[1].

IC50 & Target

IC50: 0.31 μM (AKR1C3), 73.23 μM (AKR1C2)[1]
体外研究
(In Vitro)

AKR1C3-IN-6 (Compound 1) shows antiproliferative activity with an IC50 of 81.40 ± 2.29 μM against prostate cancer cell line 22rv1[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

AKR1C3-IN-6 相关抗体:
分子量

392.33

Formula

C18H15F3N4O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献
Cell Assay

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
参考文献

AKR1C3-IN-6 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AKR1C3-IN-62137881-54-8Others22rv1prostate cancerantitumorInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-146573
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