2. Neuronal Signaling
  3. CaMK
  4. [Ala286]-Calmodulin-Dependent Protein Kinase II (281-302)

[Ala286]-Calmodulin-Dependent Protein Kinase II (281-302) 

目录号: HY-P10499
产品使用指南

摩尔计算器

[Ala286]-Calmodulin-Dependent Protein Kinase II (281-302) 是一种经过修饰的钙离子/钙调蛋白依赖性蛋白激酶II (CaMKII) 的片段，这个片段包含了 CaMKII 的活性区域，并且在 286 位点上用丙氨酸替代。[Ala286]-Calmodulin-Dependent Protein Kinase II (281-302) 可用于更有效的 CaMKII 抑制剂的开发。

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Custom Peptide Synthesis

[Ala286]-Calmodulin-Dependent Protein Kinase II (281-302) Chemical Structure

[Ala286]-Calmodulin-Dependent Protein Kinase II (281-302) Chemical Structure

CAS No. : 141055-85-8

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[Ala286]-Calmodulin-Dependent Protein Kinase II (281-302) 相关抗体

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CaMK III CaMK II

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

[Ala286]-Calmodulin-Dependent Protein Kinase II (281-302) is a modified fragment of calcium/calmodulin-dependent protein kinase II that contains the active domain of CaMKII and has an alanine substitution at position 286. [Ala286]-Calmodulin-Dependent Protein Kinase II (281-302) can be used to develop more potent CaMKII inhibitors[1].

分子量

2600.08

Formula

CSCC[C@H](N)C(N[C@@H](CC1=CN=CN1)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](C)C(N[C@@H](C(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H](CS)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@H](C(N[C@@H](CC(N)=O)C(N[C@@H](C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(NCC(N[C@@H](C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC2=CC=CC=C2)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
CAS 号
Sequence

Met-His-Arg-Gln-Glu-Ala-Val-Asp-Cys-Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala
Sequence Shortening

MHRQEAVDCLKKFNARRKLKGA
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

[Ala286]-Calmodulin-Dependent Protein Kinase II (281-302) 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

[Ala286]-Calmodulin-Dependent Protein Kinase II (281-302)141055-85-8CaMKCalmodulin-dependent protein kinasesCalmodulin-dependent kinasesPeptidesamino acid modificationprotein engineeringCaMKIIInhibitorinhibitorinhibit

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