2. 天然产物
  3. 微生物 酮、醛、酸
  4. Albizziin

Albizziin是一种氨基酸类似物，具有作为天冬酰胺合成酶的竞争抑制剂的活性。Albizziin被用于分离具有目标酶水平变化的中国仓鼠卵巢细胞突变体。Albizziin的几种突变类别可以根据对β-天冬氨酸羟肟酸的交叉抗性进行区分。有关天冬酰胺合成酶的研究表明，对albizziin的抗性可能与天冬酰胺合成酶的调节改变、酶的结构突变以及基因扩增有关。

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Albizziin Chemical Structure

Albizziin Chemical Structure

CAS No. : 585-23-9

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Other Forms of Albizziin:

Albizziin 相关抗体

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  • 生物活性

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生物活性

Albizziin is an amino acid analog with activity as a competitive inhibitor of asparagine synthetase. Albizziin has been used to isolate Chinese hamster ovary cell mutants with altered levels of the target enzyme. Several mutational classes of albizziin can be distinguished based on cross-resistance to β-aspartic hydroxamic acid. Studies on asparagine synthetase have shown that resistance to albizziin may be associated with altered regulation of asparagine synthetase, structural mutations of the enzyme, and gene amplification[1].

分子量

147.13

Formula

C4H9N3O3
CAS 号
结构分类
初始来源

D. ovoideum
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Albizziin 相关分类

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  • 稀释计算器

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Keywords:

Albizziin585-23-9OthersInhibitorinhibitorinhibit

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