2. GPCR/G Protein Neuronal Signaling
  3. 5-HT Receptor
  4. Alosetron (Hydrochloride) (Standard)

Alosetron (Hydrochloride) (Standard)  (Synonyms: GR 68755C (Standard); GR 68755 (Hydrochloride) (Standard); GR 68755X (Hydrochloride) (Standard))

目录号: HY-70050CR 纯度: ≥98%
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Alosetron (Hydrochloride) (Standard) 是 Alosetron (Hydrochloride) 的分析标准品。本产品用于研究及分析应用。 Alosetron Hydrochloride (GR 68755C) 是一种高效、高选择性的 5-HT3 受体 (5-HT3 receptor) 拮抗剂。Alosetron Hydrochloride 用于肠易激综合征 (IBS) 的研究。Alosetron Hydrochloride 阻断 5HT3 介导的豚鼠肌间和粘膜下神经元的快速去极化，IC50 在 ~55 nM。Alosetron Hydrochloride 减轻清醒或麻醉犬直肠扩张的内脏伤害性效应。具有抗炎活性。

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Alosetron (Hydrochloride) (Standard) Chemical Structure

Alosetron (Hydrochloride) (Standard) Chemical Structure

CAS No. : 122852-69-1

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规格 价格 是否有货
5 mg ￥720
询问价格 & 货期
10 mg ￥1080
询问价格 & 货期
25 mg ￥1944
询问价格 & 货期
50 mg ￥2916
询问价格 & 货期
100 mg ￥4374
询问价格 & 货期

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生物活性

Alosetron (Hydrochloride) (Standard) is the analytical standard of Alosetron (Hydrochloride). This product is intended for research and analytical applications. Alosetron Hydrochloride (GR 68755C) is a potent and highly selective serotonin 5-HT3 receptor antagonist. Alosetron Hydrochloride is used for the research of irritable bowel syndrome (IBS). Alosetron blocks the fast 5HT3-mediated depolarisation of guinea-pig myenteric and submucosal neurons, with IC50 at ~55 nM. Alosetron Hydrochloride attenuates the visceral nociceptive effect of rectal distension in conscious or anaesthetised dogs. Anti-inflammatory effects.

分子量

330.81

Formula

C17H19ClN4O
CAS 号
中文名称

阿洛司琼盐酸盐 (标准品)
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

Alosetron (Hydrochloride) (Standard) 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Alosetron (Hydrochloride) (Standard)122852-69-1GR 68755C (Standard)GR 68755 Hydrochloride (Standard)GR 68755X Hydrochloride (Standard)阿洛司琼盐酸盐 (标准品)5-HT ReceptorSerotonin Receptor5-hydroxytryptamine ReceptorInhibitorinhibitorinhibit

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