2. Anti-infection
  3. Bacterial
  4. AM4085

AM4085 是一种口服有效的 FmlH 拮抗剂，IC50 为 0.19 μM。AM4085 在小鼠肝微粒体和血浆中具有稳定性。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

AM4085 Chemical Structure

AM4085 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

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Customer Review

AM4085 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AM4085 is an orally active Antagonist for FmlH with an IC50 of 0.19 μM. AM4085 reveals metabolic stability in mouse liver microsomes and blood plasma[1].

体内研究
(In Vivo)

AM4085 在 C3H/HeN 小鼠中展现出良好的口服生物利用度[1]：

AM4085 在 C3H/HeN 小鼠体内的药代动力学分析[1]

route Dose (mg/kg) C0 (ng/mL) Cmax (ng/mL) T1/2 (h) Vdss (L/kg) CL (mL/min/kg) Tlast (h) AUC0-last (ng·h/mL) AUC0-inf (ng·h/mL) MRT0-last (h) MRT0-inf (h) AUCExtra (%) AUMCExtra (%) F (%)
iv 3 4427 - 1.47 1.42 13.6 8.0 3662 3736 1.59 1.75 1.90 10.8 -
po 10 - 1483 1.92 - - 8.0 6070 6564 3.18 3.75 7.55 21.6 52.7

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

459.39

Formula

C21H21F4NO6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

AM4085 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AM4085AM 4085AM-4085Bacterialurinary tract infectionsInhibitorinhibitorinhibit

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