1. Epigenetics PI3K/Akt/mTOR Metabolic Enzyme/Protease
  2. AMPK Acetyl-CoA Carboxylase
  3. AMPK activator 16

AMPK activator 16 (compound 6) 是一种 AMP 激活蛋白激酶 (AMPK) 抑制剂。AMPK activator 16 与 AMPK 的关键残基表现出最有效的相互作用,并显著激活 AMPK。在 N2a 细胞中,AMPK activator 16 能够增加磷酸化 AMPK (p-AMPK) 及其下游信号蛋白,如磷酸化ACC (Acetyl-CoA Carboxylase) 和磷酸化 raptor (p-raptor) 的表达。

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AMPK activator 16 Chemical Structure

AMPK activator 16 Chemical Structure

CAS No. : 2252336-04-0

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生物活性

AMPK activator 16 (compound 6) is a AMP-activated protein kinase (AMPK) inhibitor. AMPK activator 16 shows the most efficient interactions with the key residues of AMPK and demonstrates significant activation of AMPK. AMPK activator 16 increases the expression of phosphorylated AMPK (p-AMPK) and its downstream signaling proteins, such as phosphorylated ACC (Acetyl-CoA Carboxylase) (p-ACC) and phosphorylated raptor (p-raptor), in N2a cells[1].

分子量

457.93

Formula

C23H20ClNO5S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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产品名称:
AMPK activator 16
目录号:
HY-170931
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