1. Epigenetics PI3K/Akt/mTOR
  2. AMPK
  3. AMPK activator 6

AMPK activator 6 (Compound GC) 作用于HepG2 和 3T3-L1 细胞,可降低脂质含量并激活AMPK 通路。AMPK activator 6 显著抑制血清中甘油三酯 (TG)、总胆固醇 (TC)、低密度脂蛋白-C (LDL-C) 和其他生化指标的增加。AMPK activator 6 可用于非酒精性脂肪肝(NAFLD)和代谢综合征的研究。

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AMPK activator 6 Chemical Structure

AMPK activator 6 Chemical Structure

CAS No. : 189299-03-4

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AMPK activator 6 (Compound GC) reduces lipid content and activates the AMPK pathway in HepG2 and 3T3-L1 cells. AMPK activator 6 significantly suppresses the increase in triglyceride (TG) , total cholesterol (TC), low-density lipoprotein-C (LDL-C), and other biochemical indices in blood serum. AMPK activator 6 can be used for the research of non-alcoholic fatty liver disease (NAFLD) and metabolic syndrome[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HeLa IC50
18.2 μM
Compound: 3, 3'-geranylchalconaringenin
Cytotoxicity against human HeLa cells by MTT assay after 72 hrs
Cytotoxicity against human HeLa cells by MTT assay after 72 hrs
[PMID: 18611049]
分子量

408.49

Formula

C25H28O5

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

AMPK activator 6 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
AMPK activator 6
目录号:
HY-146398
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