2. Neuronal Signaling
  3. Amyloid-β
  4. Amyloid β-Protein (3-42)

Amyloid β-Protein (3-42) 是 Pyr 肽的前体。焦谷氨酸修饰的 Aβ (pEAβ) (3-42) 是阿兹海默症淀粉样板块的核心。pEAβ (3-42) 加速 Aβ(1-42) 的聚集，而 Aβ(1-42) 显著减慢 pEAβ(3-42) 的初级和次级成核。

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Custom Peptide Synthesis

Amyloid β-Protein (3-42) Chemical Structure

Amyloid β-Protein (3-42) Chemical Structure

CAS No. : 157884-74-7

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规格 价格 是否有货
500 μg ￥3600
询问价格 & 货期
1 mg ￥5440
询问价格 & 货期
5 mg 现货 询问价格 & 货期

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Amyloid β-Protein (3-42) 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

生物活性

Amyloid β-Protein (3-42) is the precursor of Pyr peptide. Pyroglutamate-modified Aβ (pEAβ) (3-42) is the core of the amyloid template block in Alzheimer's disease. pEAβ(3-42) accelerated the aggregation of Aβ(1-42), while Aβ(1-42) significantly slowed the primary and secondary nucleation of pEAβ(3-42)[1].

分子量

4327.87

Formula

C196H301N53O56S
CAS 号
性状

固体

颜色

White to off-white

Sequence

Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala
Sequence Shortening

EFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

纯度 & 产品资料

Amyloid β-Protein (3-42) 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Amyloid β-Protein (3-42)157884-74-7Amyloid-ββ-amyloid peptideAβAbetaPyr peptideamyloid blockAlzheimer's diseaseaggregationInhibitorinhibitorinhibit

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