2. Anti-infection
  3. Bacterial
  4. Anti-inflammatory agent 14

Anti-inflammatory agent 14 (compound 28) 具有抗炎活性，其对 Mtb H37Rv 的 MIC50 值为 2 μM。

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Anti-inflammatory agent 14 Chemical Structure

Anti-inflammatory agent 14 Chemical Structure

CAS No. : 894496-27-6

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Anti-inflammatory agent 14 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anti-inflammatory agent 14 (compound 28) is an anti-inflammatory agent, with a MIC50 of 2 μM for Mtb H37Rv[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
RAW264.7 CC50
≥ 200 μM
Compound: 28
Cytotoxicity against LPS-stimulated mouse RAW264.7 cells after 24 hrs by MTT assay
Cytotoxicity against LPS-stimulated mouse RAW264.7 cells after 24 hrs by MTT assay
[PMID: 34890996]
RAW264.7 IC50
13.7 μM
Compound: 28
Inhibition of NO production in mouse RAW264.7 cells incubated for 24 hrs by Griess reagent based analysis
Inhibition of NO production in mouse RAW264.7 cells incubated for 24 hrs by Griess reagent based analysis
[PMID: 34890996]
RAW264.7 IC50
20.7 μM
Compound: 28
Anti-inflammatory activity against LPS-stimulated mouse RAW264.7 cells assessed as reduction in TNFalpha protein expression level after 24 hrs by ELISA
Anti-inflammatory activity against LPS-stimulated mouse RAW264.7 cells assessed as reduction in TNFalpha protein expression level after 24 hrs by ELISA
[PMID: 34890996]
RAW264.7 IC50
33.2 μM
Compound: 28
Anti-inflammatory activity against LPS-stimulated mouse RAW264.7 cells assessed as reduction in IL1beta protein expression level after 24 hrs by ELISA
Anti-inflammatory activity against LPS-stimulated mouse RAW264.7 cells assessed as reduction in IL1beta protein expression level after 24 hrs by ELISA
[PMID: 34890996]
体外研究
(In Vitro)

Anti-inflammatory agent 14 (compound 28) inhibits IL-1β dose-dependently[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Anti-inflammatory agent 14 相关抗体:
分子量

300.38

Formula

C16H16N2O2S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Anti-inflammatory agent 14 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-inflammatory agent 14894496-27-6BacterialinflammationmycobacteriumthioureatuberculosisInhibitorinhibitorinhibit

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