2. Anti-infection
  3. Bacterial
  4. Antibacterial agent 130

Antibacterial agent 130 是一种 1,1-二酰硫半乳糖苷，用于靶向铜绿假单胞菌 (Pseudomonas aeruginosa) LecA。Antibacterial agent 130 对 LecA 具有较高的亲和力 (Kd=1 μM)。Antibacterial agent 130 具有抗菌膜活性，但缺乏杀菌活性。LecA，一种来自铜绿假单胞菌的凝集素和毒力因子，参与细菌粘附和生物膜的形成。

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Antibacterial agent 130 Chemical Structure

Antibacterial agent 130 Chemical Structure

CAS No. : 1502721-60-9

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Antibacterial agent 130 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antibacterial agent 130 is a 1,1-diarylthiogalactoside, used for targeting the Pseudomonas aeruginosa LecA. Antibacterial agent 130 shows high affinity toward LecA (Kd=1 μM). Antibacterial agent 130 has antibiofilm activity, but lacks bactericidal activity. LecA, a lectin and virulence factor from Pseudomonas aeruginosa involved in bacterial adhesion and biofilm formation[1].

体外研究
(In Vitro)

Antibacterial agent 130 (化合物 8a) (0.08-5 mM; 2-24 h) 剂量依赖性抑制细菌生物膜的形成，在 5 mM 剂量下的抑制率是 100%[1]。
Antibacterial agent 130 (0.01-5 mM; 24 h) 浓度高于1.25 mM 时对 MRC-5 细胞系 (人胎儿肺成纤维细胞) 有细胞毒性[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Antibacterial agent 130 相关抗体:
分子量

496.53

Formula

C23H28O10S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Antibacterial agent 130 相关分类

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Keywords:

Antibacterial agent 1301502721-60-9Antibacterial agent130Antibacterial agent-130BacterialInhibitorinhibitorinhibit

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