2. Anti-infection
  3. Bacterial
  4. Antibacterial agent 141

Antibacterial agent 141 (Compound B14) 对 4 种植物病原体 Xoo、Xac、Psa 和 Cmm 具有抗菌活性，EC50 值为 1.28 μM。 Antibacterial agent 141 可以抑制细胞膜的形成，改变细胞的通透性。

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Antibacterial agent 141 Chemical Structure

Antibacterial agent 141 Chemical Structure

CAS No. : 2930013-56-0

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Antibacterial agent 141 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antibacterial agent 141 (Compound B14) has antibacterial activity against four plant pathogens Xoo, Xac, Psa and Cmm, with an EC50 value of 1.28 μM. Antibacterial agent 141 can inhibit the formation of cell membrane and change cell permeability.

体外研究
(In Vitro)

Antibacterial agent 141 显著诱导 Xoo 细菌的细胞膜破裂[1]。
Antibacterial agent 141 在 Xoo 细菌中以浓度依赖性方式增加细菌膜通透性[1]。
Antibacterial agent 141 破坏 Xoo 细菌的细胞膜表面[1]。
Antibacterial agent 141 (3.2，6.4 μM) 显著降低 Xoo 细菌中 ACC、ACP 和 Fab 家族基因的表达[1]。
Antibacterial agent 141随着浓度的增加显著抑制 Xoo 生物膜的形成[1]。
Antibacterial agent 141 对 HepG2 和 HK-2 细胞毒性低[1]。
Antibacterial agent 141 (0.64-5.12 μM；3-30 h) 显著抑制 Xoo 细菌的生长[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Antibacterial agent 141 相关抗体:

Real Time qPCR

Cell Line: Xoo bacteria
Concentration: 3.2, 6.4 μM
Incubation Time:
Result: Significantly reduced the expression of ACC, ACP and Fab family genes in Xoo bacteria.

Cell Viability Assay

Cell Line: Xoo bacteria
Concentration: 0.64, 1.28, 2.56, 5.12 μM
Incubation Time: 3, 6, 9, 12, 15, 18, 21, 24, 27, 30 h
Result: Had a slight inhibitory effect on bacterial growth with the concentration of 0.64, 1.28, 2.56 μM.
Inhibited the growth of bacteria more obviously when the drug concentration reached 5.12 μM.
体内研究
(In Vivo)

Antibacterial agent 141 (200 μg/mL；7 天；单剂量) 对白叶枯病的治疗和保护活性分别为 4.64% 和 43.33%[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

414.93

Formula

C23H27ClN2O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Antibacterial agent 141 相关分类

  • 摩尔计算器

  • 稀释计算器

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antibacterial agent 1412930013-56-0Antibacterial agent141Antibacterial agent-141BacterialAntibacterialCell membraneCell permeabilityToxicityInhibitorinhibitorinhibit

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