2. Anti-infection Cell Cycle/DNA Damage
  3. Bacterial Fungal Topoisomerase
  4. Antibacterial agent 229

Antibacterial agent 229 (compound 8a) 是一种强效抗菌剂。Antibacterial agent 229 具有抗菌和抗真菌能力。Antibacterial agent 229 破坏细菌膜的完整性，插入 DNA。Antibacterial agent 229 抑制拓扑异构酶 IV (topoisomerase IV) 活性，其 IC50 值为 10.88 µM 。

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Antibacterial agent 229 Chemical Structure

Antibacterial agent 229 Chemical Structure

CAS No. : 3049500-54-8

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Antibacterial agent 229 相关抗体

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Topoisomerase Topo I Topo II

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antibacterial agent 229 (compound 8a) is a potent antibacterial agent. Antibacterial agent 229 shows antibacterial and antifungal abilities. Antibacterial agent 229 disrupts the integrity of the bacterial membrane, intercalates into DNA. Antibacterial agent 229 inhibits topoisomerase IV with an IC50 value of 10.88 µM[1].

IC50 & Target[1]

TOPO IV

10.88 μM (IC50)

体外研究
(In Vitro)

Antibacterial agent 229 (compound 8a) 表现出抗细菌和抗真菌能力，对 S. aureus ATCC 25923、S. aureus ATCC 29213、E. coli ATCC 25922、P. aeruginosa ATCC 27853、C. albicans ATCC 9002、C. albicans 和 C. parapsilosis ATCC 22019 的 MIC 值分别为 0.0377、0.0047、0.0189、0.0189、0.0189、0.0047 mM[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Antibacterial agent 229 相关抗体:
分子量

424.90

Formula

C16H14ClFN6OS2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Antibacterial agent 229 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

Antibacterial agent 2293049500-54-8Antibacterial agent229Antibacterial agent-229BacterialFungalTopoisomeraseAntibacterialantifungalStaphylococcus aureusInhibitorinhibitorinhibit

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