E Cadherin 抗体

E Cadherin Antibody is a rabbit-derived non-conjugated IgG antibody , targeting E Cadherin, with a predicted molecular weight of 97 kDa (observed band size: 135 kDa). E Cadherin Antibody can be used for WB, IHC-P, IHC-F, ICC/IF, ELISA experiment in human, mouse, rat background.

The related gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to related generate the mature glycoprotein. The calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in The related gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of The related gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of The protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. The related gene is present in a related gene cluster with other members of the cadherin family on chromosome 16.

999

Predicted band size: 97 kDa; Observed band size: 135 kDa

Affinity Purified

Non-conjugated

Unmodified

Signal Transduction

Primary Antibody; Rabbit Polyclonal Antibody

Polyclonal

Rabbit

Human, Mouse, Rat

P12830

WB: 1/500-1/1000; IHC: 1/50-1/100; IF: 1/50-1/200; ELISA: 1/10000

WB, IHC-P, IHC-F, ICC/IF, ELISA

液体

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

The antiserum was produced against synthesized peptide derived from human Cadherin.