Phospho-c-Met (Tyr1349) 抗体

Phospho-c-Met (Tyr1349) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 156 kDa, targeting to Phospho-c-Met (Tyr1349). It can be used for WB,IP assays with tag free, in the background of Human.

c-Met：该基因编码受体酪氨酸激酶蛋白家族的成员和原癌基因 MET 的产物。编码的前原蛋白经过蛋白水解处理，生成通过二硫键连接形成成熟受体的 α 和 β 亚基。β 亚基的进一步加工导致 M10 肽的形成，这已被证明可以减少肺纤维化。其配体肝细胞生长因子的结合会诱导受体的二聚化和激活，从而在细胞存活、胚胎发生以及细胞迁移和侵袭中发挥作用。该基因的突变与乳头状肾细胞癌、肝细胞癌和各种头颈癌有关。该基因的扩增和过度表达也与多种人类癌症有关。[由 RefSeq 提供，2016 年 5 月]

Free

4233

Predicted band size: 156 kDa

affinity purified

Non-conjugated

Phosphorylated

Signal Transduction

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human

P08581

WB: 1:500-1:1,000 ;IP: 1:20

WB, IP

液体

Supplied in 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol and 0.05% BSA. Preservative: 0.01% Sodium azide

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

Synthetic phosphopeptide corresponding to residues surrounding Tyr1349 of Human Met.The exact sequence is proprietary to MCE.