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  5. SLC12A1 抗体 (YA3471)

SLC12A1 抗体 (YA3471)

目录号: HY-P83742
抗体使用指南 技术支持

SLC12A1 Antibody (YA3471) 是无偶联基团的、靶向 SLC12A1 的 IgG 抗体 (克隆号：YA1403)，预测分子量为 121 kDa (实际观测：150 kDa)。SLC12A1 Antibody (YA3471) 可用于人、小鼠和大鼠背景下的 WB, IHC-P, IF-Cell, mIHC 实验。

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描述

SLC12A1 Antibody (YA3471) is a non-conjugated IgG antibody, targeting SLC12A1, with a predicted molecular weight of 121 kDa (observed band size: 150 kDa). SLC12A1 Antibody (YA3471) can be used for WB, IHC-P, IF-Cell, mIHC experiment in human, Mouse and Rat background.
研究背景

The related gene encodes a kidney-specific sodium-potassium-chloride cotransporter that is expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henle's loop and the macula densa. It plays a key role in concentrating urine and accounts for most of the NaCl resorption. It is sensitive to such diuretics as furosemide and bumetanide. Some Bartter-like syndromes result from defects in The related gene. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity in humans has not been experimentally proven.
基因 ID

6557
同用名
BSC1 antibody; Bumetanide sensitive sodium 3 antibody; Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2 antibody; Kidney specific Na K Cl symporter antibody; Kidney-specific Na-K-Cl symporter antibody; MGC48843 antibody; Na K 2Cl cotransporter antibody; NKCC2 antibody; potassiumchloride cotransporter 2 antibody; S12A1_HUMAN antibody; Slc12a1 antibody; sodium potassium chloride cotransporter 2 antibody; solute carrier family 12 (sodium/potassium/chloride transporters) antibody; Solute carrier family 12 member 1 antibody
分子量

Predicted band size: 121 kDa; Observed band size: 150 kDa
纯度

Affinity Purified
亚细胞定位

Cell membrane
偶联

Non-conjugated
修饰

Unmodified
研究领域

Signal Transduction
产品类别

Primary Antibody; Recombinant Rabbit Monoclonal Antibody
克隆性

Monoclonal, Recombinant
宿主

Rabbit
反应物种

Human, Mouse, Rat
蛋白数据库

Q13621
推荐稀释比例

WB: 1:2,000;IHC-P: 1:20,000;IF-Cell: 1:100;mIHC: 1:3,000
应用

WB, IHC-P, ICC/IF
阳性对照

Mouse kidney tissue lysate, rat kidney tissue lysate, K-562 cell lysate, mouse kidney tissue, K-562.
性状

液体
组分

Supplied in 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
保存条件 & 期限

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
运输条件

Shipping with blue ice.
同型

IgG
免疫原

Recombinant protein within Human SLC12A1 / NKCC2 aa 593-813 / 1,099.
文件资料
抗体使用指南 (1083 KB)

SLC12A1 Antibody (YA3471) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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