TCF3 / E2A 抗体 (YA1220)

TCF3 / E2A Antibody (YA1220) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1220), targeting TCF3 / E2A. TCF3 / E2A Antibody (YA1220) can be used for IHC-P experiment in human background.

The related gene encodes a member of the E protein (class I) family of helix-loop-helix transcription factors. E proteins activate transcription by binding to regulatory E-box sequences on target related genes as heterodimers or homodimers, and are inhibited by heterodimerization with inhibitor of DNA-binding (class IV) helix-loop-helix proteins. E proteins play a critical role in lymphopoiesis, and the encoded protein is required for B and T lymphocyte development. Deletion of The related gene or diminished activity of the encoded protein may play a role in lymphoid malignancies. The related gene is also involved in several chromosomal translocations that are associated with lymphoid malignancies including pre-B-cell acute lymphoblastic leukemia (t(1;19), with PBX1), childhood leukemia (t(19;19), with TFPT) and acute leukemia (t(12;19), with ZNF384). Alternatively spliced transcript variants encoding multiple isoforms have been observed for The related gene, and a pseudorelated gene of The related gene is located on the short arm of chromosome 9.

6929

Affinity Purified

Non-conjugated

Unmodified

Epigenetics and Nuclear Signaling

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human

P15923

IHC: 1/100-1/200

IHC-P

液体

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.254.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

Recombinant protein of human TCF-3