2. Apoptosis
  3. Apoptosis
  4. Anticancer agent 110

Anticancer agent 110 是一种抗癌剂，具有体外抗癌活性以及对出色抗白血病效力。Anticancer agent 110 对 K-562 系慢性粒细胞白血病细胞在纳摩尔浓度下具有高细胞毒性。Anticancer agent 110 引起 DNA 损伤，并导致细胞凋亡 (apoptosis)。

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Anticancer agent 110 Chemical Structure

Anticancer agent 110 Chemical Structure

CAS No. : 887349-03-3

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Anticancer agent 110 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anticancer agent 110 is an anticancer agent with in vitro anticancer activity and excellent anti-leukemia potency. Anticancer agent 110 is highly cytotoxic to K-562 lineage chronic myelogenous leukemia cells at nanomolar concentrations. Anticancer agent 110 causes DNA damage and leads to apoptosis[1].

体外研究
(In Vitro)

Anticancer agent 110 (化合物 3d) (0.01 μM-100 μM) 抑制白血病 K-562 细胞，IC50 为 0.7 μM[1]。
Anticancer agent 110 (70 nM、700 nM；24 h) 在 K-562 细胞中引起更高水平的 DNA 损伤[1]。
Anticancer agent 110 (70 nM、700 nM；24 h) 诱导白血病细胞形态发生促凋亡变化[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Anticancer agent 110 相关抗体:
分子量

380.40

Formula

C18H13FN6OS
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Anticancer agent 110 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anticancer agent 110887349-03-3Anticancer agent110Anticancer agent-110Apoptosisanticanceranti-leukemiaK-562DNA damageapoptosisInhibitorinhibitorinhibit

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