2. Apoptosis
  3. IAP
  4. Anticancer agent 127

Anticancer agent 127 (142D6) 是一种 IAP 抑制剂，共价靶向 XIAP、cIAP1 和 cIAP2 的 BIR3 结构域。Anticancer agent 127 靶向 XIAP、cIAP1 和 cIAP2 的 BIR3 结构域，IC50 分别为 12 nM、14 nM 和 9 nM。Anticancer agent 127 具有抗癌活性。

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Anticancer agent 127 Chemical Structure

Anticancer agent 127 Chemical Structure

CAS No. : 2410953-19-2

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Anticancer agent 127 相关抗体

Top Publications Citing Use of Products

查看 IAP 亚型特异性产品:

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cIAP cIAP-1 cIAP-2 XIAP

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anticancer agent 127 (142D6) is an IAP inhibitor that covalently targets the BIR3 domains of XIAP, cIAP1, and cIAP2. Anticancer agent 127 targets the BIR3 domains of XIAP, cIAP1, and cIAP2 with IC50s of 12 nM, 14 nM, and 9 nM, respectively. Anticancer agent 127 has anticancer effects[1].

IC50 & Target

IC50: 12 nM (XIAP-BIR3), 14 nM (cIAP1-BIR3), and 9 nM (cIAP2-BIR3)[1]
分子量

552.66

Formula

C26H37FN4O6S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Anticancer agent 127 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anticancer agent 1272410953-19-2Anticancer agent127Anticancer agent-127IAPXIAPcIAP1cIAP2BIR3 domainsInhibitorinhibitorinhibit

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