2. Others Apoptosis Autophagy
  3. Biochemical Assay Reagents Apoptosis Autophagy Ferroptosis
  4. Anticancer agent 251

Anticancer agent 251 (compound 7j) 可通过诱导细胞发生凋亡、自噬或者铁死亡的方式诱导膀胱癌细胞 T24 死亡。

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Anticancer agent 251 Chemical Structure

Anticancer agent 251 Chemical Structure

CAS No. : 1648546-79-5

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Anticancer agent 251 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anticancer agent 251 (compound 7j) can induce cell death of bladder cancer cell T24 by inducing apoptosis, autophagy or ferroptosis[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
Bel-7402 IC50
5.77 μM
Compound: 7j
Antiproliferative activity against human Bel-7402 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human Bel-7402 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
[PMID: 32827851]
MGC-803 IC50
5.21 μM
Compound: 7j
Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
[PMID: 32827851]
T-24 IC50
3.97 μM
Compound: 7j
Antiproliferative activity against human T-24 cells assessed as reduction in cell viability measured upto 72 hrs by MTT assay
Antiproliferative activity against human T-24 cells assessed as reduction in cell viability measured upto 72 hrs by MTT assay
[PMID: 32827851]
分子量

438.31

Formula

C22H17Cl2N5O
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Anticancer agent 251 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anticancer agent 2511648546-79-5Anticancer agent251Anticancer agent-251Biochemical Assay ReagentsApoptosisAutophagyFerroptosisQuinazolinyl-arylureaStructure-activity relationshipInhibitorinhibitorinhibit

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