2. Apoptosis
  3. Apoptosis
  4. Anticancer agent 39

Anticancer agent 39 (compound B12) 是济源冬凌草素 A (JOA) 的荧光衍生物，可诱导线粒体膜电位 (MMP) 的崩溃，从而诱导细胞凋亡。Anticancer agent 39 抑制细胞克隆和迁移。Anticancer agent 39 具有抗 HGC-27 细胞增殖活性 IC50 值为 0.39 μM。

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Anticancer agent 39 Chemical Structure

Anticancer agent 39 Chemical Structure

CAS No. : 2762426-00-4

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Anticancer agent 39 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

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生物活性

Anticancer agent 39 (compound B12), a fluorescent derivative of Jiyuan Oridonin A (JOA), induces the collapse of mitochondrial membrane potential (MMP)and thus induced apoptosis.Anticancer agent 39 inhibits cell cloning and migration.Anticancer agent 39 exhibits promising anti-proliferative activity against HGC-27 cells with IC50 value of 0.39 μM[1].

分子量

896.08

Formula

C50H65N5O10
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Anticancer agent 39 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anticancer agent 392762426-00-4Anticancer agent39Anticancer agent-39ApoptosisJiyuan?Oridonin?Amitochondrial membrane potentialMMPcloningmigrationproliferative activityHGC-27Inhibitorinhibitorinhibit

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