1. Anti-infection
  2. Virus Protease
  3. Anticancer agent 90

Anticancer agent 90 是一种具有抗肿瘤活性的苯并噻唑-2-噻吩 S-糖苷衍生物。Anticancer agent 90 对卵巢癌 (OVCAR-4) 和肾癌 (A498) 细胞系有较高的抑制作用。

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Anticancer agent 90 Chemical Structure

Anticancer agent 90 Chemical Structure

CAS No. : 2977251-03-7

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anticancer agent 90 is a benzothiazole-2-thiophene S-glycoside derivative with antitumor activity. Anticancer agent 90 has high inhibition against the two cell line from ovarian cancer (OVCAR-4), renal cancer (A498)[1].

体外研究
(In Vitro)

Anticancer agent 90 (compound 6d) (0.01 mM; 24 h) has low cytotoxicity, shows high inhibition against two cell lines, SK-MEL-5, OVCAR-4[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay[1]

Cell Line: FRHK-4, Hep2, BGM, Vero, and Huh 7.5 cell lines
Concentration: 0-200 μg/mL
Incubation Time: 24 hours
Result: Showed nontoxic under the doses of 100 μg/mL against FRHK-4, Hep2, BGM, Vero, and Huh 7.5 cells, respectively.

Cell Viability Assay[1]

Cell Line: SK-MEL-5, OVCAR-4, and A498
Concentration: 0.01 mM
Incubation Time: 24 hours
Result: Inhibited SK-MEL-5 and OVCAR-4 cell viability by 30.64% and 30.71%, respectively.
分子量

712.81

Formula

C33H32N2O10S3

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Anticancer agent 90 相关分类

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Anticancer agent 90
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HY-151588
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