2. Anti-infection
  3. Fungal
  4. Antifungal agent 40

Antifungal agent 40 是一种抗真菌剂，可延伸到 C.alb.CYP51 的狭窄疏水口袋 II 中。Antifungal agent 40 对 lanosterol 14α-demethylase (CYP51) 具有抑制作用。Antifungal agent 40 抑制生物膜形成。

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Antifungal agent 40 Chemical Structure

Antifungal agent 40 Chemical Structure

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Antifungal agent 40 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antifungal agent 40 is an antifungal agent which extends into the narrow hydrophobic pocket II of C.alb. CYP51. Antifungal agent 40 has an inhibitory effect on lanosterol 14α-demethylase (CYP51). Antifungal agent 40 inhibits biofilm formation[1].

IC50 & Target

CYP51[1]
体外研究
(In Vitro)

Antifungal agent 40 (compound A03, 0.25-128 μg/mL) inhibits fungal activity with MIC values of 1-64 μg/mL[1].
Antifungal agent 40 (1-8 μg/mL, 16 h) inhibits lanosterol 14α-demethylase (CYP51) of C.alb (GC-MS analysis)[1].
Antifungal agent 40 (0.5 μg/mL, 1.5-24 h) displays antibiofilm activity against FCZ-Resistant C.alb[1].
Antifungal agent 40 (0-10 μM respectively) shows cytotoxicity against HL-60, MDA-MB-231 and PC-3 cells with IC50 values of 5.18, 3.25, 0.98 μM respectively[1].
Antifungal agent 40 (2-32 μg/mL, 3 h) displays high hemolysis rate in rabbit erythrocyte[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Antifungal agent 40 相关抗体:
分子量

490.29

Formula

C22H20Cl2N4Se
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Antifungal agent 40 相关分类

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antifungal agent 40Antifungal agent40Antifungal agent-40FungalAntifungalinfectionbiofilmC.albhemolysiserythrocyteInhibitorinhibitorinhibit

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