2. Apoptosis
  3. Apoptosis
  4. Antiproliferative agent-19

Antiproliferative agent-19 (化合物 4a) 是一种抗癌剂，通过诱导凋亡对肺癌细胞发挥抗增殖作用。Antiproliferative agent-19 还可诱导细胞周期停滞在 G2/M 期。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Antiproliferative agent-19 Chemical Structure

Antiproliferative agent-19 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Customer Review

Antiproliferative agent-19 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antiproliferative agent-19 (compound 4a) is an anti-cancer agent that exerts anti-proliferative effects on lung cancer cells by inducing apoptosis. antiproliferative agent-19 also induces cell cycle arrest in the G2/M phase[1].

体外研究
(In Vitro)

Antiproliferative agent-19 (0-50 µM; 72 h) 显著抑制人非小细胞肺癌和结肠癌细胞的生存能力[1]。
Antiproliferative agent-19 (11.33 µM; 24, 48, and 72 h) 诱导 A549 细胞的亚 G1 期细胞周期停滞[1]。
Antiproliferative agent-19 (11.33 µM; 6, 24 and 48 h) 在 A549 细胞中通过内在和外在途径诱导细胞凋亡[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Antiproliferative agent-19 相关抗体:

Cell Cytotoxicity Assay[1]

Cell Line: HCT-116 and A549 cells
Concentration: 0-50 µM
Incubation Time: 72 h
Result: Inhibited the growth of HCT-116 and A549 cells with IC50 values of 12.18 and 11.33 µM, respectively.

Cell Cycle Analysis[1]

Cell Line: A549 cells
Concentration: 11.33 µM
Incubation Time: 24, 48, and 72 h
Result: Increased cells of G2 phase significantly from 3.2% (DMSO-treated cells) to 15.5% and 33.8% (cells treated with the compound for 24 and 48 h, respectively).

Apoptosis Analysis[1]

Cell Line: A549 cells
Concentration: 11.33 µM
Incubation Time: 6, 24 and 48 h
Result: Induced caspase-dependent cell death.
分子量

365.47

Formula

C26H23NO
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Antiproliferative agent-19 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antiproliferative agent-19Antiproliferative agent19Antiproliferative agent 19Apoptosisanti-proliferationapoptosiscell cycle arrestcancerG2/MHCT-116 cellA549 cellInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
Antiproliferative agent-19
目录号：
HY-152099
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z