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Antitumor agent-144 (16) 是一种抗肿瘤剂,其在L1210 和KB 细胞中的IC50 值为2.6 μM 和8.4 μM。

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Antitumor agent-144 Chemical Structure

Antitumor agent-144 Chemical Structure

CAS No. : 137346-42-0

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antitumor agent-144 (16) is an antitumor agent, with IC50 values of 2.6 μM and 8.4 μM in L1210 and KB cells, respectively[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
KB IC50
7.6 μM
Compound: 17
In vitro antitumor activity against human epidermoid carcinoma KB cells by MTT assay.
In vitro antitumor activity against human epidermoid carcinoma KB cells by MTT assay.
10.1016/0960-894X(95)00353-U
L1210 IC50
9.6 μM
Compound: 17
In vitro antitumor activity against murine lymphoma L1210 cells by MTT assay.
In vitro antitumor activity against murine lymphoma L1210 cells by MTT assay.
10.1016/0960-894X(95)00353-U
V79 IC50
19 μM
Compound: 13
Differential hypoxic cytotoxicity towards chinese hamster cells (V79) using MTT assay under anaerobic conditions
Differential hypoxic cytotoxicity towards chinese hamster cells (V79) using MTT assay under anaerobic conditions
10.1016/0960-894X(95)00352-T
V79 IC50
27 μM
Compound: 13
Differential hypoxic cytotoxicity towards chinese hamster cells (V79) using MTT assay under aerobic conditions
Differential hypoxic cytotoxicity towards chinese hamster cells (V79) using MTT assay under aerobic conditions
10.1016/0960-894X(95)00352-T
分子量

446.50

Formula

C25H26N4O4

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Antitumor agent-144 相关分类

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  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Antitumor agent-144
目录号:
HY-117708
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