2. Metabolic Enzyme/Protease Apoptosis
  3. Mitochondrial Metabolism Apoptosis
  4. Antitumor agent-159

Antitumor agent-159 (Compound 13b) 靶向线粒体并下调心磷脂水平。Antitumor agent-159 抑制癌细胞 MDA-MB-231 的增殖，在 sub-G1 期阻滞细胞周期，并诱导 MDA-MB-231 细胞凋亡 (apoptosis)。Antitumor agent-159 在 MDA-MB-231 异种移植小鼠模型中表现出抗肿瘤活性。

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Antitumor agent-159 Chemical Structure

Antitumor agent-159 Chemical Structure

CAS No. : 1611446-66-2

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规格 价格 是否有货 数量
1 mg ￥810
3 - 4 周
5 mg ￥3105
3 - 4 周
10 mg ￥5265
3 - 4 周
50 mg   询价  
100 mg   询价  

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Antitumor agent-159 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antitumor agent-159 (Compound 13b) targets the mitochondria and downregulates cardiolipin levels. Antitumor agent-159 inhibits the proliferation of cancer cell MDA-MB-231, arrests the cell cycle at sub-G1 phase, and induces apoptosis in MDA-MB-231. Antitumor agent-159 exhibits antitumor efficacy in MDA-MB-231 xenograft mouse models[1].

分子量

493.00

Formula

C24H36ClF3N2O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Antitumor agent-159 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antitumor agent-1591611446-66-2Antitumor agent159Antitumor agent 159Mitochondrial MetabolismApoptosisMDA-MB-231breast cancerBALB/c mouseInhibitorinhibitorinhibit

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