1. Cell Cycle/DNA Damage
  2. G-quadruplex
  3. Antitumor agent-84

Antitumor agent-84 (compound 21a) 是一种 G-quadruplex (G4) 配体,具有稳定不同 G4-DNA 结构的能力。Antitumor agent-84 具有高效的抗肿瘤特性。

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Antitumor agent-84 Chemical Structure

Antitumor agent-84 Chemical Structure

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antitumor agent-84 (compound 21a) is a G-quadruplex (G4)-ligand with the ability to stabilize different G4-DNA structures. Antitumor agent-84 has highly effective anti-tumor properties[1].

体外研究
(In Vitro)

Antitumor agent-84 稳定 c-MYC Pu24T,c-MYC Pu22,CKit1,CKit2,KRAS 和 G4 的 DNA 结构[1]
Antitumor agent-84 (1-10000 nM) 抑制肿瘤类器官和癌症激活的成纤维细胞 (CAF),IC50 值分别为 161 和 2515 nM[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

417.55

Formula

C24H31N7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Antitumor agent-84
目录号:
HY-152537
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