2. Anti-infection
  3. Flavivirus
  4. Antiviral agent 19

Antiviral agent 19 (Compound 3) 是一种选择性的 Zika 病毒抑制剂，EC50 为 1.3 µM。Antiviral agent 19 具有低细胞毒性。

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Antiviral agent 19 Chemical Structure

Antiviral agent 19 Chemical Structure

CAS No. : 1807887-16-6

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Antiviral agent 19 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antiviral agent 19 (Compound 3) is a selective inhibitor against Zika virus infection with an EC50 of 1.3 µM. Antiviral agent 19 has low cytotoxicity[1].

IC50 & Target

EC50: 1.3 µM (Zika virus)
细胞效力
(Cellular Effect)
Cell Line Type Value Description References
SNB-19 EC50
1.3 μM
Compound: 3
Antiviral activity against Zika virus PRVABC-59 infected in human SNB19 cells assessed as reduction in viral titer incubated for 24 hrs by viral titer assay
Antiviral activity against Zika virus PRVABC-59 infected in human SNB19 cells assessed as reduction in viral titer incubated for 24 hrs by viral titer assay
[PMID: 31838328]
SNB-19 CC50
22.7 μM
Compound: 3
Cytotoxicity against human SNB19 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay
Cytotoxicity against human SNB19 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay
[PMID: 31838328]
SNB-19 CC50
22.7 μM
Compound: 146
Cytotoxicity against human SNB-19 cells incubated for 24 hrs
Cytotoxicity against human SNB-19 cells incubated for 24 hrs
[PMID: 33609889]
Vero CC50
20.8 μM
Compound: 3
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
[PMID: 31838328]
Vero CC50
20.8 μM
Compound: 146
Cytotoxicity against african green monkey Vero cells incubated for 48 hrs
Cytotoxicity against african green monkey Vero cells incubated for 48 hrs
[PMID: 33609889]
分子量

477.59

Formula

C29H35NO5
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Antiviral agent 19 相关分类

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质量   浓度   体积   分子量 *
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This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antiviral agent 191807887-16-6Antiviral agent19Antiviral agent-19FlavivirusZika virusantiviralInhibitorinhibitorinhibit

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目录号：
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