2. Anti-infection
  3. Virus Protease Influenza Virus SARS-CoV
  4. Antiviral agent 54

Antiviral agent 54 (compound 33) 是一种广谱的和具有口服活性的抗病毒剂。Antiviral agent 54 显示 ZIKV，HCoV-OC43 和甲型流感病毒 (influenza A virus (IVA)) 的抗病毒活性。Antiviral agent 54 会降低 ZIKV RNA 和蛋白质水平。

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Antiviral agent 54 Chemical Structure

Antiviral agent 54 Chemical Structure

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Antiviral agent 54 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antiviral agent 54 (compound 33) is a broad-spectrum and orally active antiviral agent. Antiviral agent 54 shows antiviral activity for ZIKV, HCoV-OC43 and influenza A virus (IVA). Antiviral agent 54 decreases the ZIKV RNA and protein level[1].

IC50 & Target

EC50: 0.39 µM (ZIKV); 2.28 µM (HCoV-OC43); 2.69 µM (influenza A)[1]
体外研究
(In Vitro)

Antiviral agent 54 (compound 33) (5, 2.5, 1.25, 0.625 µM; 48 h) 以剂量依赖性方式降低 ZIKV NS5 蛋白和 RNA 水平[1]。
Antiviral agent 54 对 ZIKV、HCoV-OC43 和甲型流感病毒 (IVA) 具有抗病毒活性，EC50 值分别为 0.39、2.28、2.69 µM[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Antiviral agent 54 相关抗体:

Western Blot Analysis[1]

Cell Line: HUVEC cells
Concentration: 5, 2.5, 1.25, 0.625 µM
Incubation Time: 48 h
Result: Decreased the ZIKV NS5 protein level in a dose-dependent manner.

RT-PCR[1]

Cell Line: HUVEC cells
Concentration: 10 µM
Incubation Time: 48 h
Result: Decreased the ZIKV RNA level in a dose-dependent manner.
分子量

411.59

Formula

C23H37N7
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Antiviral agent 54 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antiviral agent 54Antiviral agent54Antiviral agent-54Virus ProteaseInfluenza VirusSARS-CoVSARS coronavirusHUVEC cellsZIKV RNAantiviralorally activeHCoV-OC43 and influenza A virus (IVA)Inhibitorinhibitorinhibit

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目录号：
HY-161454
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