2. Others
  3. Others
  4. AO-022

AO-022 是一种有效的 TALDO1 变构抑制剂。AO-022 可降低 vimentin 和 snail 的蛋白表达。AO-022 具有抗增殖活性和抗肿瘤活性。AO-022 具有用于乳腺癌研究的潜力。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

AO-022 Chemical Structure

AO-022 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Customer Review

AO-022 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AO-022 is a potent TALDO1 allosteric inhibitor. AO-022 decreases the expression of vimentin and snail. AO-022 shows antiproliferative activity and antitumor activity. AO-022 has the potential for the research of breast cancer[1].

IC50 & Target

TALDO1[1]
体外研究
(In Vitro)

AO-022 (5, 10, 20, 40, 80 µM; 24 h) 以剂量依赖性方式抑制 MDA-MB-231 细胞中的细胞活力[1]。
AO-022 (0, 2.5,5, 10, 20 µM; 24 h) 以剂量依赖性方式降 vimentin 和 snail 的蛋白表达[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

AO-022 相关抗体:

Western Blot Analysis[1]

Cell Line: MDA-MB-231 cells
Concentration: 0, 2.5,5, 10, 20 µM
Incubation Time: 24 h
Result: Inhibited the protein expression of vimentin and snail in a dose-dependent manner.
体内研究
(In Vivo)

AO-022 (50 mg/kg; i.p.; every other day for fourteen days) 在小鼠体内显示出抗肿瘤活性[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 6-week-old female nude mice (MDA-MB-231 cells)[1]
Dosage: 50 mg/kg
Administration: I.p.; every other day for fourteen days
Result: Significantly reduced tumor volume and tumor weight.
分子量

413.87

Formula

C21H16ClNO4S
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

AO-022 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AO-022AO022AO 022OthersMDA-MB-231 cellsantiproliferativeantitumorbreast cancervimentinsnailInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
AO-022
目录号：
HY-159130
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z