2. Metabolic Enzyme/Protease
  3. Aminopeptidase
  4. Apstatin

Apstatin 是一种有效的氨基肽酶 P (aminopeptidase P (APP)) 抑制剂，对大鼠和人类 APP 的 Ki 值分别为 2.6、0.64 µM。Apstatin 具有心脏保护作用。

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Apstatin Chemical Structure

Apstatin Chemical Structure

CAS No. : 160470-73-5

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Apstatin 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Apstatin is a potent aminopeptidase P (APP) inhibitor with Ki values of 2.6, 0.64 µM for rat and human APP, respectively. Apstatin shows cardioprotection[1][2].

IC50 & Target

IC50: 2.6 µM (rat APP); 0.64 µM (human APP)[1]
体内研究
(In Vivo)

Apstatin (1 mg/kg; i.v.; 5 min before ischaemia) 可减少急性心肌缺血模型中的心肌梗塞面积 (IS)[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 270-310 g, Male Wistar rats[1]
Dosage: 1 mg/kg
Administration: I.v.; 5 min before ischaemia
Result: Significantly reduced infarct size (IS) in acute myocardial ischaemia.
分子量

459.54

Formula

C23H33N5O5
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Apstatin 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Apstatin160470-73-5Aminopeptidasemyocardial infarct sizecardioprotectionInhibitorinhibitorinhibit

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