1. Membrane Transporter/Ion Channel
  2. Monocarboxylate Transporter
  3. AR-C117977

AR-C117977 是一种有效的单羧酸转运蛋白 (monocarboxylate transporter (MCT1)) 抑制剂。AR-C117977 可延长皮肤和心脏移植物的存活时间。AR-C117977 可部分抑制主动脉移植中移植动脉硬化的发展,但无法抑制移植后的同种抗体产生。AR-C117977 在体内表现出有效的免疫抑制特性,可有效预防小鼠急性而非慢性的移植排斥。

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AR-C117977 Chemical Structure

AR-C117977 Chemical Structure

CAS No. : 216685-07-3

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查看 Monocarboxylate Transporter 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AR-C117977 is a potent monocarboxylate transporter (MCT1) inhibitor. AR-C117977 prolongs the survival of skin and heart sllograft. AR-C117977 inhibits the development of transplant arteriosclerosis in aortic allografts partially, but was unable to inhibit alloantibody production after transplantation. AR-C117977 shows potent immunosuppressive properties in vivo effectively preventing acute but not chronic allograft rejection in the mouse[1].

分子量

468.63

Formula

C25H28N2O3S2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
AR-C117977
目录号:
HY-114602
需求量: