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  4. Arecaidine propargyl ester hydrobromide

Arecaidine propargyl ester hydrobromide 

目录号: HY-134061
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Arecaidine propargyl ester hydrobromide是一种M2型毒蕈碱乙酰胆碱受体的激动剂，具有抑制肿瘤细胞增殖的活性。Arecaidine propargyl ester hydrobromide的应用显示出它在体外能够降低卵巢癌细胞的数量，并且在特定浓度下诱导细胞凋亡及活性氧 (ROS) 的产生。Arecaidine propargyl ester hydrobromide还可以使细胞在细胞周期的G2/M阶段停滞，并增加异常有丝分裂的百分比。Arecaidine propargyl ester hydrobromide对具有较高M2受体水平的卵巢表面上皮细胞的致敏性高于癌细胞。Arecaidine propargyl ester hydrobromide在与自然生理状态下的心血管系统相互作用时，表现出降低动脉血压的效果，显示其潜在的药理应用。

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Arecaidine propargyl ester hydrobromide Chemical Structure

Arecaidine propargyl ester hydrobromide Chemical Structure

CAS No. : 116511-28-5

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Arecaidine propargyl ester hydrobromide 相关抗体

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生物活性

Arecaidine propargyl ester hydrobromide is an agonist of M2 muscarinic acetylcholine receptors and has the activity of inhibiting tumor cell proliferation. The application of arecaidine propargyl ester hydrobromide has shown that it can reduce the number of ovarian cancer cells in vitro and induce apoptosis and the production of reactive oxygen species (ROS) at specific concentrations. Arecaidine propargyl ester hydrobromide can also arrest cells at the G2/M phase of the cell cycle and increase the percentage of abnormal mitosis. Arecaidine propargyl ester hydrobromide is more sensitizing to ovarian surface epithelial cells with higher M2 receptor levels than to cancer cells. Arecaidine propargyl ester hydrobromide exhibits the effect of lowering arterial blood pressure when interacting with the cardiovascular system in a natural physiological state, indicating its potential pharmacological application[1].

分子量

260.13

Formula

C10H14BrNO2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Arecaidine propargyl ester hydrobromide 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

Arecaidine propargyl ester116511-28-5OthersInhibitorinhibitorinhibit

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