1. Stem Cell/Wnt
  2. β-catenin Wnt
  3. aStAx-35R

aStAx-35R 是一种钉书肽,可拮抗 β-catenin 的核形式并抑制 Wnt 信号传导。aStAx-35R 竞争性抑制 β-catenin 与 TCF4 的结合。aStAx-35R 选择性地诱导 Wnt 依赖性癌细胞的生长抑制。

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Custom Peptide Synthesis

aStAx-35R Chemical Structure

aStAx-35R Chemical Structure

CAS No. : 1418863-17-8

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aStAx-35R 的其他形式现货产品:

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Other Forms of aStAx-35R:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

aStAx-35R, a stapled peptide, antagonizes nuclear form of β-catenin and inhibits Wnt signaling. aStAx-35R inhibits competitively the binding of β-catenin to TCF4. aStAx-35R selectively induces growth inhibition of Wnt-dependent cancer cells[1].

分子量

2392.86

Formula

C111H178N40O20

CAS 号
Sequence Shortening

Ac-RRWPR-S5-ILD-S5-HVRRVWR-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
aStAx-35R
目录号:
HY-P10392
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