1. Membrane Transporter/Ion Channel Neuronal Signaling
  2. GABA Receptor
  3. Atagabalin

Atagabalin  (Synonyms: PD 0200390)

目录号: HY-14856
产品使用指南

Atagabalin (PD 0200390) 一种选择性的 GABA (γ-氨基丁酸) 受体激动剂,具有抗焦虑和镇静的作用。Atagabalin 通过结合到 GABA 受体的 α2δ 亚基上,增强 GABA 受体的活性,从而增加 GABA 介导的抑制作用。这种增强作用导致神经元的兴奋性降低,有助于减少焦虑和改善睡眠。Atagabalin 可用于神经精神类疾病,焦虑或睡眠障碍中的研究。

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Atagabalin Chemical Structure

Atagabalin Chemical Structure

CAS No. : 223445-75-8

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生物活性

Atagabalin (PD 0200390) is a selective GABA (gamma-aminobutyric acid) receptor agonist with antianxiety and sedative effects. Atagabalin enhances the activity of the GABA receptor by binding to the α2δ subunit of the GABA receptor, thereby increasing the GABA mediated inhibition. This enhancement results in reduced excitability of neurons, helping to reduce anxiety and improve sleep. Atagabalin can be used to study neuropsychiatric disorders, anxiety or sleep disorders[1].

分子量

185.26

Formula

C10H19NO2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Atagabalin
目录号:
HY-14856
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